![]() ![]() The zona fasciculata, the middle zone, contains foamy-looking cells in columns that are responsible for the production of glucocorticoids, predominantly cortisol, which increases blood sugar levels via gluconeogenesis, suppresses the immune system, and aids in metabolism. The zona glomerulosa, the outer zone, contains clustered cells that produce mineralocorticoids, mainly aldosterone, which regulates blood pressure and electrolyte balance. For your exam, something high-yield to keep in mind is that the cortex is composed of 3 zones. ![]() Each adrenal gland has two main components: the cortex and the medulla. Ok, so both seem to have some type of adrenal masses. In Dan’s case, CT detected a mass in the left adrenal cortex. In Jessica’s case, imaging detected a mass in the right adrenal cortex. Abdominal CT scans were obtained for both. Dan is not taking any medications but he’s complaining of severe lumbar pain on the left side. ![]() He is also hypertensive and hyperglycemic. The other person is 38-year-old Dan, who is obese and has an abnormally round face. Examination is unremarkable and she doesn’t have any history of kidney disease. First is Jessica, who comes in with lumbar pain, anuria, and constipation. While doing your rounds, you see two individuals.
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